Caffeine and definition: How does it work and how to use this ingredient for fat loss?

Jan 12, 2026AMIX STORE
Cafeína y definición: ¿Cómo funciona y cómo usar este ingrediente para la pérdida de grasa?

Caffeine is one of the most used ingredients in sports supplements and products focused on fat loss. Its popularity is no coincidence: it is widely studied, improves physical performance and can help increase fat loss when used correctly.

In this article we explain how caffeine works in fat loss, its synergy with other ingredients, when to take it and if it is really worth including it in your body definition strategy.

What is caffeine and why is it used in fat loss supplements?

Caffeine: A 100% natural stimulant

Caffeine is a natural stimulant that acts on the central nervous system. It is found naturally in foods and drinks such as:

  • Coffee
  • Green Tea
  • cocoa 
  • Guarana
  • Yerba mate

Your ability to increase energy, concentration and energy expenditure make it a key substance for sports performance and fat loss

Caffeine in sports and thermogenic supplements

In the field of supplementation, caffeine It can also be found in the form of anhydrous caffeine., a concentrated and quickly absorbed version and is a common ingredient in supplements such as:

  • Pre-workouts
  • Thermogenic
  • Fat Loss Supplements

Caffeine and fat loss: How does it interfere?

Caffeine is one of the few ingredients with solid scientific backing for performance enhancement and increased caloric expenditure, which explains its widespread use both in athletes and in people seeking to reduce their fat. 

Caffeine interferes with sports performance in different ways that contribute to training better and, therefore, stimulating fat loss. 

Stimulation of the central nervous system 

caffeine blocks adenosine receptors, reducing the feeling of fatigue and increasing alertness. This allows you to train with greater intensity and for longer, a key factor in burning more calories.

Increased metabolism and thermogenesis

One of the most interesting effects of caffeine is its ability to increase thermogenesis, that is, the production of body heat. This translates into greater energy expenditure, even at rest.

Mobilization of fatty acids and lipolysis

Caffeine stimulates release of catecholamines such as adrenaline, which favors lipolysis (release of fatty acids from adipose tissue). These fatty acids can be used as a source of energy during exercise.

Effect of caffeine on daily caloric expenditure

Consumed strategically, Caffeine may slightly increase total caloric expenditure for the day, contributing to creating an energy deficit more favorable for fat loss.

Caffeine and sports performance: Train better and lose fat

The effects of caffeine help you train more efficiently, intervening in different aspects. 

Improved training performance and intensity

Numerous studies show that caffeine improves strength, endurance, power and performance in high intensity training. 

Better training in terms of performance will imply greater calorie burning and greater muscle stimulation. 

Reduction of fatigue and perception of effort

caffeine reduces perception of effort, allowing you to maintain higher rhythms and complete more demanding sessions, especially in phases of caloric deficit.

Increased fat oxidation during exercise

In aerobic and moderate intensity workouts, caffeine can increase the oxidation of fats, favoring their use as fuel.

Caffeine and other ingredients for fat loss

When it comes to supplementation, caffeine is often combined with other ingredients to enhance the effects of fat loss.

Caffeine and L-carnitine

L-carnitine helps transport of fatty acids, complementing the lipolytic effect of caffeine

Caffeine and green tea

Green tea provides catechins that enhance thermogenesis and prolong the effect of caffeine. 

Caffeine and synephrine

Caffeine and synephrine can be combined in thermogenics to increase energy expenditure, although they should be used with caution

Combination of ingredients in thermogenic supplements: Advantages of using them

The well-formulated fat burners combine several ingredients for a synergistic effect, optimizing results without the need for excessive doses of caffeine.

A complete thermogenic supplement in terms of composition is the AMIX ThermoCore, which combines in its formulation ingredients such as caffeine, caffeine anhydrous and guarana extract, further reinforcing the effects of this compound on alertness, performance and the perception of effort and fatigue. 

THERMOCORE 30 CAPS

BUY THERMOCORE FROM AMIX

Possible side effects of caffeine

Some of the most common side effects of caffeine are nervousness, tachycardia or insomniaHowever, as long as it is consumed in the recommended doses, caffeine is a completely safe ingredient for healthy people. 

In order to ensure safe consumption, in the case of people with problems such as hypertension, anxiety, heart problems or high sensitivity, it is recommended that they consult with a professional before using it. 

Conclusion: Does caffeine really help you lose fat?

According to scientific evidence, Caffeine helps increase energy expenditure and fat oxidation, although it must be combined with an adequate caloric deficit and training for this fat loss to be significant. 

Therefore, used in moderation and within a structured diet and training plan, caffeine can be a great ally in fat loss processes. The key will be in adjust the dose, respect breaks and always prioritize fundamental habits. 

Toni Ortega profile picture

Toni Ortega

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Redactor especialista en suplementación y nutrición deportiva.

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